Collagen XXV alpha 1 Products

Description

Antibodies against senile plaque (SP) amyloid obtained a clone which labeled amyloid fibrils in SPs and reacted with approximately 50/100 kDa polypeptides in Alzheimer's disease (AD) brains. The antigen was identified as CLAC (collagen-like Alzheimer amyloid plaque component), and its precursor as CLAC-P/collagen type XXV. Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bound to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD.

Bioinformatics

Entrez	77018 Mouse 84570 Human
Uniprot	AAH36669.1 Human NM_198721 Human NP_942014 Human NP_942014.1 Human Q9BXS0 Human
Product By Gene ID	84570
Alternate Names	Alzheimer disease amyloid-associated protein AMY CLAC CLACP CLAC-P Collagen 25 collagen alpha-1(XXV) chain collagen, type XXV, alpha 1 Collagen-25 collagen-like Alzheimer amyloid plaque component collagenous Alzheimer amyloid plaque component

Research Areas for Collagen XXV alpha 1

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Neuroscience