Chromogranin B Antibody

Product Discontinued

Chromogranin B Antibody Summary

• Immunogen: C-terminal 15 amino acids of chromogranin B conjugated to ovalbumin.
• Localization: Neuroendocrine and endocrine secretory granules
• Specificity: NB600-1516 recognises chromogranin B.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CHGB
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:100-1:500
  • Western Blot 1:100-1:500
• Theoretical MW: 78 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Whole antisera with PBS
• Preservative: No Preservative
• Purity: Unpurified

Alternate Names for Chromogranin B Antibody

• CgB
• CHGB
• chromogranin B (secretogranin 1)
• Chromogranin B
• Chromogranin-B
• SCG1
• SCG1sgI
• secretogranin B
• Secretogranin I
• secretogranin-1
• SgI

Background

The Chromogranin B gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. Thisprotein may serve as a precursor for regulatory peptides. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Chromogranin B Antibody (NB600-1516)(2)

Publications using NB600-1516

• Sun M, Watanabe T, Bochimoto H et al. Multiple sorting systems for secretory granules ensure the regulated secretion of Peptide hormones Traffic 2013-02-01 [PMID: 23171199] (WB, ICC/IF, Mouse)
• de Jong EK, Vinet J, Stanulovic VS et al. Expression, transport, axonal sorting of neuronal CCL21 in large dense-core vesicles. FASEB J :fj07-101907. 2008-01-01 [PMID: 18697841]

Bioinformatics

• Gene Symbol: CHGB
• Entrez:
  • 1114(Human)
  • 12653(Mouse)
  • 24259(Rat)
• Uniprot:
  • P05060()