CDK2 Antibody (2B6)

Immunohistochemistry-Paraffin: Cdk2 Antibody (2B6) [NBP2-26448] - IHC analysis of Cdk2 formalin-fixed paraffin embedded human spleen using NBP2-26448.

Product Discontinued

CDK2 Antibody (2B6) Summary

• Immunogen: BALB/C mice were injected with a human recombinant cdk2 protein.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: CDK2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:25-1:50
  • Western Blot 1:100-500

Reactivity Notes

human, mouse, rat. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS with BSA
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for CDK2 Antibody (2B6)

• cdc2-related protein kinase
• CDK2
• cell devision kinase 2
• Cell division protein kinase 2
• cyclin-dependent kinase 2
• EC 2.7.11
• EC 2.7.11.22
• p33 protein kinase
• p33(CDK2)

Background

Principal Names: Cyclin-dependent kinase 2 Official Gene Symbol: CDK2 Gene ID: 1017 (Human) Gene Map Locus: 12q13 (Human). Cyclin-dependent kinase 2 (CDK2) a serine/threonine protein kinase, is a member of a highly conserved family of protein kinases that regulate the eukaryotic cell cycle. The protein kinase is homologous to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. For activity, it requires association with a cyclins which act as the positive regulatory subunit.It can complex with cyclins A, E, D1, and D3. Cyclin E-Cdk2 kinase is active in the G1 and S phases of the cell cycle and is important for the progression from G1 to S phase. The levels of Cyclin A-Cdk2 are maximal at the G1/S transition and both Cdk2 and Cyclin A associate with DNA in the initiation complex during replication. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDK2