CD155/PVR [p Ser123, p Ser124] Antibody (TX56) [Allophycocyanin]

Images

 
Flow Cytometry: CD155/PVR [p Ser123, p Ser124] Antibody (TX56) [Allophycocyanin] [NBP2-00075] - Staining of C57BL/6 thymocytes with Anti-Mouse CD4, Anti-Mouse CD8a and 0.5 ug of Rat IgG2a kappa Isotype Control APC (blue ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
TX56
Clonality
Monoclonal
Host
Rat
Concentration
0.2 mg/ml

Order Details

CD155/PVR [p Ser123, p Ser124] Antibody (TX56) [Allophycocyanin] Summary

Immunogen
The immunogen for this antibody is CD155.
Modification
p Ser123, p Ser124
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
PVR
Purity
Protein A or G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Conjugate
Allophycocyanin
Format
Allophycocyanin (A=620-650, E=660-670)
Buffer
Aqueous buffer, may contain carrier protein/stabilizer (proprietary)
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
This TX56 antibody has been tested by flow cytometric analysis on mouse thymocytes. This can be used at less than or equal to 1 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 uL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Reactivity Notes

Mouse

Alternate Names for CD155/PVR [p Ser123, p Ser124] Antibody (TX56) [Allophycocyanin]

  • CD155 antigen
  • CD155
  • CD155/PVR
  • HVED
  • NECL5
  • Necl-5
  • nectin-like 5
  • Nectin-like protein 5
  • poliovirus receptor
  • PVR
  • PVS
  • PVSFLJ25946
  • Tage4

Background

This TX56 monoclonal antibody reacts with mouse CD155 (also known as poliovirus receptor or PVR), a member of the Ig superfamily of nectins and nectin-like proteins. CD155 is expressed on thymocytes (e.g. CD4+CD8+ and CD4+ cells), peripheral T and B lymphocytes (e.g. regulatory T cells, activated T cells, marginal zone B cells, and plasma cells), natural killer (NK) cells, dendritic cells (e.g. mature and activated), and monocytes. CD155 interacts with other nectins, including Nectin-3 and the extraceullar matrix protein vitronectin, the adhesion molecule CD226/DNAM-1, and the NK cell receptor CD96. CD155 plays a role in cell-cell adhesion, including formation of adherens junctions, cell migration, polarization, and NK-mediated cytotoxicity. In humans, but not in mice, CD155 is the receptor for poliovirus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol PVR
Entrez
Uniprot

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