Cav1.2 [p Ser1928] Antibody

Product Discontinued

Cav1.2 [p Ser1928] Antibody Summary

• Description: Add diH20 for desired concentration.
• Immunogen: Synthetic peptide derived from C-term part of the human protein containing phosphoserine 1928.
• Modification: p Ser1928
• Specificity: Antiserum reacts with human 2221 kDa phospho-S1928 protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CACNA1C
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Antiserum
• Preservative: No Preservative
• Purity: Unpurified

Alternate Names for Cav1.2 [p Ser1928] Antibody

• alpha-1 subunit
• CACH2
• CACN2
• CACNA1C
• CACNL1A1
• calcium channel, voltage-dependent, L type, alpha 1C subunit
• cardic dihydropyridine-sensitive, alpha-1 subunit
• Cav1.2
• CCHL1A1
• L type, alpha 1 polypeptide, isoform 1, cardic muscle
• L type, alpha-1 polypeptide, isoform 1, cardiac muscle
• splice variant 10*

Background

CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by CACNA1C binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CACNA1C