Cathepsin V Antibody (182021) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 182021
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

Cathepsin V Antibody (182021) [Alexa Fluor® 532] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Cathepsin V
  Val18-Val334
  Accession # O60911
• Specificity: Detects human Cathepsin V in direct ELISAs and Western blots. In direct ELISAs, no cross‑reactivity with recombinant human (rh) Cathepsin B, C, F, K, L, O, S, or Z is observed. In Western blots, less than 5% cross‑reactivity with rhCathepsin&nbs
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Cathepsin V Antibody (182021) [Alexa Fluor® 532]

• Cathepsin L2
• Cathepsin U
• Cathepsin V
• CATL2
• CTSL2
• CTSUcathepsin L2, preproprotein
• CTSVMGC125957
• EC 3.4.22
• EC 3.4.22.43

Background

Cathepsin V, also known as cathepsin L2 and cathepsin U, is a lysosomal cysteine protease expressed in the thymus, testis, and corneal epithelium. It may play a role in tumor progression since it is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues. Additionally, it may be involved in corneal physiology. The amino acid sequence of human Cathepsin V shares 99%, 83% and 76% identical with that of chimpanzee, dog and mouse/rat, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.