CARD11/CARMA1 Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: 0.2 mg/ml

CARD11/CARMA1 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 14 amino acids at the carboxy terminus of the human CARD11/CARMA1 protein.

  Source: Synthetic

  (Accession #: Q9BXL7)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: CARD11
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-77219.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for CARD11/CARMA1 Antibody Blocking Peptide

• BIMP3
• BIMP3card-maguk protein 1
• CARD11
• CARD-containing MAGUK protein 1
• Carma 1
• CARMA1
• CARMA1bcl10-interacting maguk protein 3
• caspase recruitment domain family, member 11
• caspase recruitment domain-containing protein 11
• MGC133069

Background

CARD11 belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CARD11