Carboxypeptidase E/CPE Antibody (420709) [mFluor Violet 500 SE]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 420709
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

Carboxypeptidase E/CPE Antibody (420709) [mFluor Violet 500 SE] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Carboxypeptidase E/CPE
  Arg42-Ser453
  Accession # P16870
• Specificity: Detects human Carboxypeptidase E/CPE in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) CPA1, rhCPA2, rhCPB1, or recombinant mouse CPA4 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: CPE
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Carboxypeptidase E/CPE Antibody (420709) [mFluor Violet 500 SE]

• Carboxypeptidase E
• Carboxypeptidase H
• CPE
• CPH
• CPH-1
• EC 3.4.17
• EC 3.4.17.10
• Enkephalin convertase
• Prohormone-processing carboxypeptidase

Background

Carboxypeptidase H encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CPE