CaMKK alpha Antibody [Alexa Fluor™ Plus 405]

• Reactivity: Hu, Rt
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor Plus 405

CaMKK alpha Antibody [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects endogenous human and rat CaMKK alpha in Western blots. In Western blots, this antibody does not cross-react with recombinant human CaMKK beta .
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CaMKK alpha Antibody [Alexa Fluor™ Plus 405]

• calcium/calmodulin-dependent protein kinase kinase 1
• calcium/calmodulin-dependent protein kinase kinase 1, alpha
• Calcium/calmodulin-dependent protein kinase kinase alpha
• CaM-kinase IV kinase
• CaM-kinase kinase 1
• CaM-kinase kinase alpha
• CaM-KK 1
• CAMKK alpha protein
• CaMKK alpha
• CaM-KK alpha
• CaMKK1
• CAMKKACaMKK 1
• DKFZp761M0423
• EC 2.7.11
• EC 2.7.11.17
• MGC34095

Background

The calcium/calmodulin (CaM) kinase signaling cascade includes the upstream kinases CaM kinase kinase alpha (CaMKK alpha ; also known as CaMKK1) and CaMKK beta (CaMKK2), and their substrates, the output kinases CaMKI and CaMKIV. Largely by activation of the transcription factor CREB, the CaM kinase cascade is implicated in neuronal development and long-term memory formation. In addition, CaMKK alpha is known to modulate skeletal muscle glucose uptake, and is upregulated during retinoic acid-induced neutrophil maturation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.