CaM Kinase II delta Antibody (438422) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: WB
• Clone: 438422
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

CaM Kinase II delta Antibody (438422) [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant human CaM Kinase IIδ
  Ala402-Lys478
  Accession # Q13557
• Specificity: Detects endogenous human CaM Kinase IIδ isoforms in Western blots. In Western blots, this antibody does not cross-react with recombinant human CaMKII alpha , CaMKII beta , or CaMKII gamma .
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CaM Kinase II delta Antibody (438422) [Alexa Fluor® 350]

• calcium/calmodulin-dependent protein kinase (CaM kinase) II delta
• calcium/calmodulin-dependent protein kinase II delta
• calcium/calmodulin-dependent protein kinase type II delta chain
• calcium/calmodulin-dependent protein kinase type II subunit delta
• CaM kinase II delta subunit
• CaM Kinase II delta
• CaM kinase II subunit delta
• CAMK2D
• CAMKD
• CaMK-II delta subunit
• CaMK-II subunit delta
• CaM-kinase II delta chain
• DKFZp686G23119
• DKFZp686I2288
• EC 2.7.11
• EC 2.7.11.17
• MGC44911

Background

Calcium/calmodulin-dependent protein kinase type II delta (CaMKIIδ) belongs to a family of multifunctional serine/threonine kinases activated in response to increases in intracellular calcium. There are 4 CaMKII isozymes, alpha , beta , gamma , and δ, and each can yield several isoforms through alternative splicing. CaMKII isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. CaMKIIδ expression is ubiquitous and has been identified as the predominant CaMKII isozyme in the heart, where it is implicated in the development of cardiac hypertrophy and heart failure.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.