Calsyntenin-1 Antibody (S07-8H2)

Images

 
Western Blot: Calsyntenin-1 Antibody (S07-8H2) [NBP3-19850] - Western blot detection of Calsyntenin-1 in Hela (Lane 1), CHO-K1 (Lane 2) cell lysates using NBP3-19850 (1:1000 diluted). Predicted band size: 110kDa. ...read more
Immunohistochemistry-Paraffin: Calsyntenin-1 Antibody (S07-8H2) [NBP3-19850] - Immunohistochemistry of Calsyntenin-1 in paraffin-embedded Human colon cancer tissue using NBP3-19850 at dilution 1/50

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clone
S07-8H2
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.3 mg/ml

Order Details

Calsyntenin-1 Antibody (S07-8H2) Summary

Description
Novus Biologicals Rabbit Calsyntenin-1 Antibody (S07-8H2) (NBP3-19850) is a recombinant monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide of human Calsyntenin-1 (Uniprot # O94985)
Source
HEK293
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
CLSTN1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1/50
  • Immunohistochemistry-Paraffin
  • Western Blot 1/1000
Theoretical MW
115 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
Preservative
0.01% Sodium Azide
Concentration
0.3 mg/ml
Purity
Affinity purified

Alternate Names for Calsyntenin-1 Antibody (S07-8H2)

  • alcadein alpha 1
  • Alcadein-alpha
  • ALC-ALPHA
  • alcalpha1
  • alcalpha2
  • Alzheimer-related cadherin-like protein
  • cadherin-related family member 12
  • calsyntenin 1
  • Calsyntenin1
  • Calsyntenin-1
  • CDHR12
  • CLSTN1
  • CS1
  • CSTN1
  • FLJ32258
  • KIAA0911alcadein-alpha
  • Non-classical cadherin XB31alpha
  • non-classical cadherin XB31alpha1
  • PIK3CD
  • XB31alpha

Background

CLSTN1 (calsyntenin 1) is mainly expressed in brain tissues and to a lesser degree in heart, skeletal muscle and the placenta. It accumulates in dystrophic neurites around the amyloid core of Alzheimer disease senile plaques. The protein induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. It is involved in complex formation with APBA2 and APP, stabilizing APP metabolism and enhancing APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. It may also modulate calcium-mediated postsynaptic signals.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CLSTN1