Calsyntenin-1 Products

Antibodies
Calsyntenin-1 Antibody
Calsyntenin-1 Antibody
AF5346
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Conjugate Catalog # Availability Size Price
Calsyntenin-1 Antibody
Calsyntenin-1 Antibody
NBP1-85706
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Calsyntenin-1 Antibody
Calsyntenin-1 Antibody
H00022883-D01P
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Lysates
Calsyntenin-1 Overexpression ...
Calsyntenin-1 Overexpression Lysat...
H00022883-T02
Applications: WB
Proteins
Calsyntenin-1 Recombinant Pro ...
Calsyntenin-1 Recombinant Protein
H00022883-P01
Species: Hu
Applications: WB, ELISA, PA
Calsyntenin-1 Partial Recombi ...
Calsyntenin-1 Partial Recombinant ...
H00022883-Q02
Species: Hu
Applications: WB, ELISA, PA
Calsyntenin-1 Partial Recombi ...
Calsyntenin-1 Partial Recombinant ...
H00022883-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Calsyntenin-1 RNAi
Calsyntenin-1 RNAi
H00022883-R02
Species: Hu
Calsyntenin-1 RNAi
Calsyntenin-1 RNAi
H00022883-R01
Species: Hu

Description

CLSTN1 (calsyntenin 1) is mainly expressed in brain tissues and to a lesser degree in heart, skeletal muscle and the placenta. It accumulates in dystrophic neurites around the amyloid core of Alzheimer disease senile plaques. The protein induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. It is involved in complex formation with APBA2 and APP, stabilizing APP metabolism and enhancing APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. It may also modulate calcium-mediated postsynaptic signals.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 22883
Alternate Names
  • XB31alpha
  • CS1
  • PIK3CD
  • Alcadein-alpha
  • Alc-alpha
  • FLJ32258
  • non-classical cadherin XB31alpha1
  • ALC-ALPHA
  • calsyntenin-1
  • Non-classical cadherin XB31alpha
  • cadherin-related family member 12
  • Alzheimer-related cadherin-like protein
  • alcalpha2
  • CSTN1
  • alcalpha1
  • CDHR12
  • KIAA0911alcadein-alpha
  • alcadein alpha 1
  • calsyntenin 1

PTMs for Calsyntenin-1

Learn more about PTMs related to Calsyntenin-1.

Methylation
Phosphorylation
Cleavage

Bioinformatics Tool for Calsyntenin-1

Discover related pathways, diseases and genes to Calsyntenin-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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