Calsenilin Antibody (011) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: ELISA
• Clone: 011
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 488

Calsenilin Antibody (011) [Alexa Fluor® 488] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human Calsenilin (Uniprot#: Q9Y2W7-1; Met1-Ile256).
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: KCNIP3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Calsenilin Antibody (011) [Alexa Fluor® 488]

• calsenilin
• calsenilin, presenilin-binding protein, EF hand transcription factor
• CSEN MGC18289
• DREAM
• DREAMA-type potassium channel modulatory protein 3
• KCHIP3 DRE-antagonist modulator
• KChIP3
• Kv channel interacting protein 3, calsenilin
• Kv channel-interacting protein 3
• potassium channel interacting protein 3

Background

The human prodynorphin gene, which is involved in memory acquisition and pain, is regulated by its downstream regulatory element (DRE). The DRE acts as a location-dependent gene silencer. DREAM is a transcriptional repressor, DRE-antagonist modulator. It is the first known Ca2+ binding protein that binds to DNA and regulates transcription.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNIP3