BCCIP Antibody

Images

 
Western Blot: BCCIP Antibody [H00056647-B01P] - Analysis of BCCIP expression in transfected 293T cell line by BCCIP polyclonal antibody. Lane 1: BCCIP transfected lysate(34.54 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: BCCIP Antibody [H00056647-B01P] - Analysis of purified antibody to BCCIP on HeLa cell. (antibody concentration 10 ug/ml)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

BCCIP Antibody Summary

Immunogen
BCCIP (AAH09771, 1 a.a. ~ 314 a.a) full-length human protein.MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAEKNNSKKKPSNKKKAALMFANAEEEF
Specificity
BCCIP - BRCA2 and CDKN1A interacting protein,
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
BCCIP
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for BCCIP Antibody

  • BCCIPalpha
  • BRCA2 and CDKN1A interacting protein
  • BRCA2 and CDKN1A-interacting protein
  • BRCA2 and Cip1/p21 interacting protein
  • cdk inhibitor p21 binding protein
  • P21- and CDK-associated protein 1
  • Protein TOK-1
  • TOK-1
  • TOK-1alpha
  • TOK1BCCIPbeta
  • TOK-1beta

Background

This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol BCCIP
Entrez
Uniprot