ATP2C1 Antibody (4G12)

Western Blot: ATP2C1 Antibody (4G12) [NBP1-47467] - Western blot analysis using ATP2C1 mouse mAb against human recombinant ATP2C1.

Immunohistochemistry: ATP2C1 Antibody (4G12) [NBP1-47467] - Immunohistochemical analysis of paraffin-embedded human ovarian cancer (left) and breast cancer (right) tissues using ATP2C1 mouse mAb with DAB staining.

Western Blot: ATP2C1 Antibody (4G12) [NBP1-47467] - Western blot analysis using ATP2C1 mouse mAb against A431 (1), Hela (2) and HEK293 (3) cell lysate.

• Reactivity: Hu, Pm, Pm
• Applications: WB, ELISA, IHC
• Clone: 4G12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

ATP2C1 Antibody (4G12) Summary

• Description: Novus Biologicals Mouse ATP2C1 Antibody (4G12) (NBP1-47467) is a monoclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Purified recombinant fragment of ATP2C1 expressed in E. Coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ATP2C1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:200-1:1000
  • Western Blot 1:500-1:2000
• Theoretical MW: 100 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, Monkey

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: 0.03% Sodium Azide
• Purity: Unpurified

Alternate Names for ATP2C1 Antibody (4G12)

• ATPase, Ca++ transporting, type 2C, member 1
• BCPM
• benign chronic pemphigus (Hailey-Hailey disease)
• Ca(2+)-sequestering
• calcium-transporting ATPase type 2C member 1
• EC 3.6.3
• HHD
• hSPCA1
• HUSSY-28
• PMR1L
• secretory pathway Ca2+/Mn2+ ATPase 1

Background

The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATP2C1