ATOH7 Antibody

Product Discontinued

ATOH7 Antibody Summary

• Immunogen: Peptide with sequence CEQRGRDHPYLP corresponding to internal region according to Uniprot Mouse NP_058560.1.
• Epitope: CEQRGRDHPYLP
• Predicted Species: Mouse (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ATOH7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
• Application Notes: WB: Preliminary experiments gave bands at approx. 50 kDa band and 38 kDa band in mouse eye and rat Optical Nerve lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 16.9 kDa band according to NP_058560.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for ATOH7 Antibody

• ATH5
• atonal homolog 7 (Drosophila)
• BHLHA13
• bHLHa13protein atonal homolog 7
• Class A basic helix-loop-helix protein 13
• hATH5
• Helix-loop-helix protein hATH-5
• Math5

Background

ATOH7 is a member of the family of basic helix-loop-helix (bHLH) proteins with similarity to Drosophila'atonal,' a proneural bHLH gene that controls photoreceptor development (Brown et al., 2002 (PubMed11889557)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ATOH7 Antibody (NBP1-06023)(1)

Publication using NBP1-06023

• Brown NL, Dagenais SL, Chen CM, Glaser T. Molecular characterization and mapping of ATOH7, a human atonal homolog with apredicted role in retinal ganglion cell development. Mamm Genome 2002-02-01 [PMID: 11889557]

Bioinformatics

• Gene Symbol: ATOH7
• Entrez:
  • 53404(Mouse)
  • 365564(Rat)
• Uniprot:
  • NP_058560.1(Mouse)