Western Blot: ATF6 beta Antibody [NBP1-91687] - Analysis in human cell line SK-MEL-30 and human cell line PC-3.
Immunohistochemistry-Paraffin: ATF6 beta Antibody [NBP1-91687] - Staining of human placenta shows moderate nuclear positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: ATF6 beta Antibody [NBP1-91687] - Staining of human Fallopian tube shows moderate nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: ATF6 beta Antibody [NBP1-91687] - Staining of human testis shows strong nuclear and cytoplasmic positivity in Leydig cells.
Immunohistochemistry-Paraffin: ATF6 beta Antibody [NBP1-91687] - Staining of human lymph node shows moderate nuclear positivity in non-germinal center cells.
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Datasheet
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ATF6 beta Antibody Summary
Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: KPVVLTTVPMPSRAVPPSTTVLLQSLVQPPPVSPVVLIQGAIRVQPEGPAPSLPRPERKSIVPAPMPGNSCPPEVDAKLLKRQQR
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ATF6B
Purity
Immunogen affinity purified
Innovator's Reward
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ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6beta homodimer or an ATF-6alpha/beta heterodimer. Binding of the ATF-6beta homodimer or ATF-6alpha/beta heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription. Human ATF-6beta maps to 1q22-q23 gene locus.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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