ATF6 beta Antibody

Images

 
Western Blot: ATF6 beta Antibody [NBP1-91687] - Analysis in human cell line SK-MEL-30 and human cell line PC-3.
Immunohistochemistry-Paraffin: ATF6 beta Antibody [NBP1-91687] - Staining of human placenta shows moderate nuclear positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: ATF6 beta Antibody [NBP1-91687] - Staining of human Fallopian tube shows moderate nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: ATF6 beta Antibody [NBP1-91687] - Staining of human testis shows strong nuclear and cytoplasmic positivity in Leydig cells.
Immunohistochemistry-Paraffin: ATF6 beta Antibody [NBP1-91687] - Staining of human lymph node shows moderate nuclear positivity in non-germinal center cells.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

ATF6 beta Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: KPVVLTTVPMPSRAVPPSTTVLLQSLVQPPPVSPVVLIQGAIRVQPEGPAPSLPRPERKSIVPAPMPGNSCPPEVDAKLLKRQQR
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ATF6B
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control
HeLa DTT Treated / Untreated Cell Lysate
Publications
Read Publications using
NBP1-91687 in the following applications:

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (86%). Reactivity indentified in Mouse in PMID (29186574)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for ATF6 beta Antibody

  • activating transcription factor 6 betacAMP-dependent transcription factor ATF-6 beta
  • ATF6-beta
  • cAMP response element-binding protein-related protein
  • cAMP responsive element binding protein-like 1
  • CREBL1CREB-RP
  • Creb-related protein
  • Creb-rp
  • cyclic AMP-dependent transcription factor ATF-6 beta
  • FLJ10066
  • G13cAMP-responsive element-binding protein-like 1
  • Protein G13

Background

ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6beta homodimer or an ATF-6alpha/beta heterodimer. Binding of the ATF-6beta homodimer or ATF-6alpha/beta heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription. Human ATF-6beta maps to 1q22-q23 gene locus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ATF6 beta Antibody (NBP1-91687)(2)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: IF/IHC, IHC-P.


Filter By Application
IF/IHC
(1)
IHC-P
(1)
All Applications
Filter By Species
Human
(1)
Mouse
(1)
All Species

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Product General Protocols

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Video Protocols

WB Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ATF6B