Asparaginase Assay Kit (Colorimetric/Fluorometric)

Asparaginase Assay Kit (Fluorometric) [KA1429] - The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.

Asparaginase Assay Kit (Fluorometric) [KA1429] - Asparaginase activity positive control test.

Product Discontinued

Asparaginase Assay Kit (Colorimetric/Fluorometric) Summary

• Description: Quality control test: Standard Curve Asparaginase Activity Assay Kit is a colorimetric and fluorometric method for assaying the activity of asparaginase.
• Specificity: This kit can be used with both colorimetric and fluorometric detection systems.
• Assay Type: Colorimetric/Fluorometric
• Sample Volume: 2-10 uL
• Kit Type: Assay Kit (Colorimetric/Fluorometric)
• Gene: ASPG

Applications/Dilutions

• Dilutions:
  • Functional

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Asparaginase Assay Kit (Colorimetric/Fluorometric)

• AnsA
• AnsB
• Asparaginase
• ASPG
• C14orf76
• Colaspase
• Cytoplasmic asparaginase I
• L ASNase I
• L ASNase II
• L asparaginase 1
• L asparaginase 2
• L asparaginase I
• L asparaginase II precursor
• L asparaginase II
• L asparagine amidohydrolase I
• L asparagine amidohydrolase II

Background

Asparaginase is a homotetramer that catalyzes the hydrolysis of asparagine to aspartic acid and ammonia and exhibits about a 2-4% activity on glutamine and 5% on D-asparagine. The enzyme has been used to reduce acrylamide, a suspected carcinogen, produced in fried starchy food products and to treat acute lymphoblastic leukemia and some other hematopoietic neoplasms (e.g. multiple myeloma). Metabolization of asparagine prevents acrylamide formation in fried foods (Maillard reaction). The enzyme's antineoplastic effects are based on the inability of cancer cells (unlike healthy cells) to synthesize asparagine. However, the enzyme is not without some antigenicity and toxicity so it is very important to measure its activity in biological samples or monitor its activity during therapy

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: ASPG