Asparaginase Products

Description

Asparaginase is a homotetramer that catalyzes the hydrolysis of asparagine to aspartic acid and ammonia and exhibits about a 2-4% activity on glutamine and 5% on D-asparagine. The enzyme has been used to reduce acrylamide, a suspected carcinogen, produced in fried starchy food products and to treat acute lymphoblastic leukemia and some other hematopoietic neoplasms (e.g. multiple myeloma). Metabolization of asparagine prevents acrylamide formation in fried foods (Maillard reaction). The enzyme's antineoplastic effects are based on the inability of cancer cells (unlike healthy cells) to synthesize asparagine. However, the enzyme is not without some antigenicity and toxicity so it is very important to measure its activity in biological samples or monitor its activity during therapy

Bioinformatics

Product By Gene ID	374569
Alternate Names	AnsA AnsB Asparaginase ASPG C14orf76 Colaspase Cytoplasmic asparaginase I L ASNase I L ASNase II L asparaginase 1 L asparaginase 2 L asparaginase I L asparaginase II precursor L asparaginase II L asparagine amidohydrolase I L asparagine amidohydrolase II

Research Areas for Asparaginase

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Neuronal Cell Markers
Neuroscience
Neurotransmission