ASB2 Antibody

Western Blot: ASB2 Antibody [NB100-56638] - Analysis of Asb-2 in HL60 cell lysate using this antibody at 1:1000 dilution.

Product Discontinued

ASB2 Antibody Summary

• Immunogen: This polyclonal antibody was raised against synthetic peptides containing amino acids 75-93 and 348-368 of human Asb-2 protein. Human spleen lysate can be used as a positive control. It should cross react with mouse and rat Asb-2, based on amino acid sequences used.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ASB2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:1000
• Control:

  Human Spleen Whole Tissue Lysate (Adult Whole Normal)

Reactivity Notes

Predicted to react with Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera with PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Purity: Unpurified

Alternate Names for ASB2 Antibody

• ankyrin repeat and SOCS box containing 2
• ankyrin repeat and SOCS box protein 2
• ankyrin repeat and SOCS box-containing protein 2a
• ASB-2ankyrin repeat and SOCS box-containing 2
• MGC40044

Background

The ankyrin repeat and SOCS box-containing (Asb) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy-terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. Asb-2 has been found to induce growth inhibition and chromatin condensation in myeloid leukemia cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ASB2
• Entrez:
  • 51676(Human)
• Uniprot:
  • Q96Q27(Human)