ARHGAP1 Antibody

Product Discontinued

ARHGAP1 Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human CDC42 GTPase-activating protein using the numbering given in entry NP_004299.1 (GeneID 392).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ARHGAP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:2000-1:10000
• Control:

  ARHGAP1 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ARHGAP1 Antibody

• ARHGAP1
• CDC42 GTPase-activating protein
• CDC42GAP
• CDC42GAPp50-RhoGAP
• GTPase-activating protein rhoOGAP
• p50rhoGAP
• Rho GTPase activating protein 1
• rho GTPase-activating protein 1
• RhoGAP
• RHOGAP1Cdc42GAP
• Rho-related small GTPase protein activator
• Rho-type GTPase-activating protein 1

Background

Cdc42 GTPase-activating protein (Cdc42GAP) is also known as p50RhoGAP and ARHGAP1. Cdc42GAP functions as a negative regulator of the Rho GTPase, Cdc42, by catalyzing the hydrolysis of GTP to GDP by Cdc42. Cdc42 activity is proposed to be involved in multiple cellular activities such as motility, survival, and genomic stability. Alternative names for Cdc42GAP include Rho GTPase-activating protein 1, Rho-type GTPase-activating protein 1, Rho-related small GTPase protein activator, RHOGAP, and RHOGAP1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARHGAP1
• Entrez:
  • 392(Human)
  • 228359(Mouse)
• Uniprot:
  • NP_004299.1(Human)