Aquaporin-2 Antibody [Alexa Fluor™ Plus 488]

• Reactivity: Hu, Mu, Rt, Po, Bv, Sh
• Applications: WB, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 488

Aquaporin-2 Antibody [Alexa Fluor™ Plus 488] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Synthetic peptide made to a C-terminus portion of rat Aquaporin-2 (within residues 200-271). [Swiss-Prot# P34080]
• Localization: Cell membrane
• Predicted Species: Porcine (100%), Bovine (100%), Sheep (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: AQP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB110-74682. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

Use in Rat reported in scientific literature (PMID:33634832).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Aquaporin-2 Antibody [Alexa Fluor™ Plus 488]

• ADH water channel
• AQP-2
• AQP-CD
• aquaporin 2 (collecting duct)
• aquaporin-2
• aquaporin-CD
• Collecting duct water channel protein
• MGC34501
• Water channel protein for renal collecting duct
• water-channel aquaporin 2
• WCH-CD

Background

Aquaporin 2 (AQP2) is a membrane protein that is involved in plasma membrane water transport in the renal collecting duct. Specifically, AQP2 forms a water-specific channel, providing the renal collecting duct plasma membranes with a high permeability to water and thereby permitting osmosis.

Aquaporin-2 antibodies serve as membrane markers and are useful for renal function studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AQP2