Recombinant Rat Apolipoprotein A-I/ApoA1 Protein Summary
Description |
A partial recombinant protein corresponding to 235 residues of APOA1 (NP_036870, 235 amino acids). Source: E. coli |
Preparation Method |
Escherichia coli expression system |
Protein/Peptide Type |
Recombinant Protein |
Gene |
APOA1 |
Applications/Dilutions
Dilutions |
|
Application Notes |
This product is useful for SDS-PAGE. |
Reactivity Notes
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
Lyophilized from sterile solution with no additives |
Preservative |
No Preservative |
Reconstitution Instructions |
Reconstitute with sterilized water to desired concentration. |
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Recombinant Rat Apolipoprotein A-I/ApoA1 Protein
Background
Apolipoprotein A1 (apo A1) is the major polypeptide of the human plasma high density lipoprotein (HDL). The structure and function of the apo A1 gene are of interest because of the inverse correlation shown between HDL levels and coronary heart disease (1). The 267 amino acid precursor initially undergoes intracellular co-translational proteolytic cleavage into proapoA-I. ProapoA-I is secreted from the cell and was isolated from thoracic duct lymph in the apoA-I1 isoform position. Results indicate that apo A1 is present in human plasma, and undergoes post-translational proteolytic cleavage to mature plasma apoA-I (2). Cleavage of this protein with cyanogen bromide yields four fragments designated in the order of elution from Bio-Gel P-30 as CNBr I, II, III, and IV (3).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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