Apolipoprotein A-I/ApoA1 Products

Description

This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq]

Bioinformatics

Entrez	335 Human
Uniprot	NP_000030.1 Human
Product By Gene ID	335
Alternate Names	Alp-1 APOA1 Apo-AI apoA-I Apolipoprotein A1 Apolipoprotein AI Apolipoprotein A-I Brp-14 Ltw-1 Lvtw-1 MGC117399 Sep-1 Sep-2

Research Areas for Apolipoprotein A-I/ApoA1

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