ApoE4 Recombinant Protein


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Product Details

Reactivity HuSpecies Glossary

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ApoE4 Recombinant Protein Summary

A recombinant protein corresponding to 300 amino acids of Human ApoE4

Source: E. coli

Amino Acid Sequence: The amino acid sequence of this product is not available.
E. coli
Endotoxin Note
<0.1 ng/ug

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
Sterile filtered and with no additives.
Reconstitution Instructions
Reconstitute with deionized water to a final concentration of 0.1 - 1.0 mg/ml.


After reconstituted, dilute further with other aqueous solutions, and stored at 4C for 1 week or -20C for future usage.

Alternate Names for ApoE4 Recombinant Protein

  • Apo-E
  • apolipoprotein E
  • apolipoprotein E3
  • late onset)
  • MGC1571


ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE is an important constituent of all plasma lipoproteins. It's interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. It also binds with the LDL receptor (apo B/E). Defects in ApoE are a cause of hyperlipoproteinemia type III. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Individuals heterozygous for the ApoE4 allele are at higher risk of late-onset Alzheimer's disease. Recombinant human ApoE4 is a 34.4 kDa protein containing 300 amino acid residues (Accession No. AAB59397). This protein has a N-terminal His-tag.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Contact Information

Product PDFs


Gene Symbol APOE

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