APLP-1 Antibody (354008) [Janelia Fluor® 635]

Product Discontinued

APLP-1 Antibody (354008) [Janelia Fluor® 635] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human APLP-1
  Gln34-Glu580 (predicted)
  Accession # P51693
• Specificity: Detects human APLP-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant mouse APLP‑1 is observed and no cross-reactivity with recombinant human APLP‑2 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: APLP1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for APLP-1 Antibody (354008) [Janelia Fluor® 635]

• amyloid beta (A4) precursor-like protein 1
• amyloid precursor-like protein 1
• amyloid-like protein 1
• APLP1
• APLP-1
• APLPAPLP-1

Background

APLP1, or Amyloid-like protein 1, contains two similar isoforms weighing approximately 72 kDa each, and is involved in postsynaptic function and signal transduction activation. Disease research is currently being conducted on APLP1 and its relation to chronic fatigue syndrome, lissencephaly, neuronitis, infertility, neurodegeneration, pharyngitis, cerebritis, and neuroblastoma. The protein is not linked to specific pathways, but it does interact with ZNF24, TK1, TSC22D1, EEF1A1, and GDF9.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: APLP1