AP2 alpha Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC

AP2 alpha Antibody Blocking Peptide Summary

• Description: A Human AP2 alpha antibody blocking peptide
  
  Source: Synthetic (Accession #: O95782)
  
  Store vial at -20C prior to opening. Aliquot contents and freeze at -20C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4C as an undiluted liquid. Dilute only prior to immediate use.
• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: TFAP2A
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This product should be used at 1.0 ug per 1.0 ul of antiserum in per assay.

Packaging, Storage & Formulations

• Storage: Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Preservative: 0.01% Sodium Azide
• Purity: >95%

Alternate Names for AP2 alpha Antibody Blocking Peptide

• Activating enhancer-binding protein 2-alpha
• Activator protein 2
• AP-2 transcription factor
• AP2-alpha
• AP2TFAP-2alpha
• AP-2transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha)
• BOFS
• FLJ51761
• TFAP2
• transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
• transcription factor AP-2-alpha

Background

AP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for AP2 alpha Protein (NBP1-96941)(1)

Publication using NBP1-96941

• Asuthkar S, Gondi CS, Nalla AK et al. Urokinase-type Plasminogen Activator Receptor (uPAR)-mediated Regulation of WNT/?-Catenin Signaling Is Enhanced in Irradiated Medulloblastoma Cells J Biol Chem 2012-06-08 [PMID: 22511755] (EMSA)

Bioinformatics

• Gene Symbol: TFAP2A
• Uniprot:
  • O95782(Human)