AMFR/gp78 Antibody [Janelia Fluor® 585]

Product Discontinued

AMFR/gp78 Antibody [Janelia Fluor® 585] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human AMFR/gp78 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: AMFR
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for AMFR/gp78 Antibody [Janelia Fluor® 585]

• AMF receptor
• AMF receptor, isoform 1
• AMF receptor, isoform 2
• AMFR
• autocrine motility factor receptor
• Autocrine motility factor receptor, isoform 2
• gp78
• RING finger protein 45
• RNF45
• RNF45EC 6.3.2.-

Background

AMFR (Autocrine motility factor receptor, isoform 2) is specific receptor for the autocrine motility factor. AMFR possesses ubiquitin ligase activity and can target both itself and other proteins including CD3D and APOB for proteasomal degradation. AMFR mediates tumor invasion and metastasis. The protein interacts with UBE2G2/UBC7 through a region distinct from the RING finger.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AMFR