AMFR/gp78 Antibody [DyLight 755]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 755

AMFR/gp78 Antibody [DyLight 755] Summary

• Immunogen: The immunogen for this product maps to a region between residue 500 and 550 of human Autocrine Motility Factor Receptor using the numbering given in entry NP_001135.3 (GeneID 267).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: AMFR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for AMFR/gp78 Antibody [DyLight 755]

• AMF receptor
• AMF receptor, isoform 1
• AMF receptor, isoform 2
• AMFR
• autocrine motility factor receptor
• Autocrine motility factor receptor, isoform 2
• gp78
• RING finger protein 45
• RNF45
• RNF45EC 6.3.2.-

Background

AMFR (Autocrine motility factor receptor, isoform 2) is specific receptor for the autocrine motility factor. AMFR possesses ubiquitin ligase activity and can target both itself and other proteins including CD3D and APOB for proteasomal degradation. AMFR mediates tumor invasion and metastasis. The protein interacts with UBE2G2/UBC7 through a region distinct from the RING finger.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AMFR