alpha-2C Adrenergic R/ADRA2C Antibody

Immunohistochemistry-Paraffin: alpha-2C Adrenergic R/ADRA2C Antibody [NLS3990] - Anti-ADRA2C antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: alpha-2C Adrenergic R/ADRA2C Antibody [NLS3990] - Staining of Human Brain, Neurons of Area CA1

Immunohistochemistry-Paraffin: alpha-2C Adrenergic R/ADRA2C Antibody [NLS3990] - Analysis of anti-ADRA2C antibody with human brain, glioblastoma.

Product Discontinued

alpha-2C Adrenergic R/ADRA2C Antibody Summary

• Immunogen: Synthetic 18 amino acid peptide from 2nd extracellular domain of human ADRA2C.
• Specificity: Human ADRA2C. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Mouse (94%), Rat (94%), Canine (94%), Bovine (94%), Guinea Pig (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ADRA2C
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 15-30 ug/ml
• Control:

  alpha-2C Adrenergic R/ADRA2C Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Hamster (89%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for alpha-2C Adrenergic R/ADRA2C Antibody

• a-2C AdrenergicR
• ADRA2C
• ADRA2L2
• ADRA2L2alpha-2CAR
• ADRA2RL2
• ADRARL2
• adrenergic, alpha-2C-, receptor
• Alpha-2 adrenergic receptor subtype C4
• alpha2-AR-C4
• alpha-2C Adrenergic R
• alpha-2C adrenergic receptor
• alpha2C AdrenergicR
• Alpha-2C adrenoceptor
• Alpha-2C adrenoreceptor
• alpha-2C-adrenergic receptor
• ALPHA2CAR
• Alpha-2CAR

Background

The Alpha 2c- Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2c-Adrenoceptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express ADRA2C. ESTs have been isolated from heart and placenta, as well as mixed heart/melanocyte/uterus libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADRA2C
• Entrez:
  • 152(Human)