AKAP9 Antibody

Product Discontinued

AKAP9 Antibody Summary

• Immunogen: Peptide with sequence QRKAQSDGQSPSKK-C corresponding to N-Terminus according to NP_005742.4, NP_671714.1.
• Epitope: N Terminus
• Specificity: This antibody is expected to recognize isoforms 2 and 3 (NP_005742.4; NP_671714.1)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: AKAP9
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:64000
• Application Notes: WB: Not yet tested - Our standard WB protocol would not expect to reliably detect proteins as large as the calculated size of 453 kDa band according to NP_005742.4.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for AKAP9 Antibody

• A kinase (PRKA) anchor protein (yotiao) 9
• AKAP 350
• AKAP 450
• AKAP350A-kinase anchor protein 450 kDa
• AKAP450A-kinase anchor protein 350 kDa
• AKAP-9
• Centrosome- and Golgi-localized PKN-associated protein
• CG-NAPAKAP 120-like protein
• hgAKAP 350
• HYPERION
• KIAA0803A-kinase anchor protein 9
• MU-RMS-40.16A
• PRKA9AKAP9-BRAF fusion protein
• Protein hyperion
• protein kinase A anchoring protein 9
• Protein kinase A-anchoring protein 9
• Protein yotiao
• YOTIAOkinase N-associated protein

Background

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in many isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for AKAP9 Antibody (NBP1-47205)(1)

Publication using NBP1-47205

• Frank B, Wiestler M, Kropp S et al. Association of a common AKAP9 variant with breast cancer risk: a collaborative analysis. J Natl Cancer Inst 2008-03-19 [PMID: 18334708]

Bioinformatics

• Gene Symbol: AKAP9
• Entrez:
  • 10142(Human)
• Uniprot:
  • NP_005742.4(Human)