ADAM33 Antibody (219515) [DyLight 488]

• Reactivity: Mu
• Applications: WB, IP
• Clone: 219515
• Clonality: Monoclonal
• Host: Rat
• Conjugate: DyLight 488

ADAM33 Antibody (219515) [DyLight 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse ADAM33 Ectodomain
  Glu205-Ala702
  Accession # Q923W9
• Specificity: Detects mouse ADAM33 Ectodomain in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse ADAM9, 10, 15, recombinant human (rh) ADAM8, rhTACE/ADAM17, rhADAM19, or rhADAM33 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Gene: ADAM33
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ADAM33 Antibody (219515) [DyLight 488]

• a disintegrin and metalloprotease 33
• a disintegrin and metalloproteinase domain 33
• ADAM 33
• ADAM metallopeptidase domain 33
• ADAM33
• C20orf153
• chromosome 20 open reading frame 153
• disintegrin and metalloproteinase domain-containing protein 33
• disintegrin and reprolysin metalloproteinase family protein
• dJ964F7.1
• DKFZp434K0521
• EC 3.4.24.-
• FLJ35308
• FLJ36751
• MGC149823
• MGC71889

Background

ADAM33 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADAM33