ADAM23 Antibody (504425) [Janelia Fluor® 549]

• Reactivity: Hu
• Applications: IHC
• Clone: 504425
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 549

ADAM23 Antibody (504425) [Janelia Fluor® 549] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human ADAM23
  Ser60-His585
  Accession # O75077
• Specificity: Detects human ADAM23 in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: ADAM23
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ADAM23 Antibody (504425) [Janelia Fluor® 549]

• a disintegrin and metalloproteinase domain 23
• ADAM metallopeptidase domain 23
• ADAM23
• disintegrin and metalloproteinase domain-containing protein 23
• MDC3
• MDC-3
• MDC3ADAM 23
• MDC-L
• Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3

Background

ADAM23 is a non-catalytic metalloprotease-like protein. It is highly expressed in the brain, primarily in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole, and weakly expressed in the heart. 3 isoforms are produced by alternative splicing, alpha, beta and gamma. ADAM23 may play a role in cell-cell and cell-matrix interactions. May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADAM23