Recombinant Mouse ACBP Isoform 2 His Protein

SDS-Page: Recombinant Mouse ACBP Isoform 2 Protein [NBP2-61996] - 15% SDS-PAGE (3ug)

• Reactivity: Mu
• Applications: PAGE
• Concentration: 1 mg/ml

Recombinant Mouse ACBP Isoform 2 His Protein Summary

• Description: A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 1-87 of Mouse ACBP
  
  

  Source:E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSQAEFD KAAEEVKRLK TQPTDEEMLF IYSHFKQATV GDVNTDRPGL LDLKGKAKWD SWNKLKGTSK ESAMKTYVEK VDELKKKYGI

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: DBI
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 12.4 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >95%, by SDS-PAGE

Alternate Names for Recombinant Mouse ACBP Isoform 2 His Protein

• ACBP
• acyl-Coenzyme A binding domain containing 1
• acyl-Coenzyme A bindingprotein)
• CCK-RP
• cholecystokinin-releasing peptide, trypsin-sensitive
• DBI
• diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
• Diazepam-binding inhibitor
• Endozepine
• EP
• GABA receptor modulator
• MGC70414

Background

ACBP encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. ACBP is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: DBI