ABCD4 Antibody

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Western Blot: ABCD4 Antibody [NBP1-20872] - (0.3ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected with chemiluminescence.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

ABCD4 Antibody Summary

Immunogen
Peptide with sequence C-RDDIDNPDQRISQD corresponding to internal region according to NP_005041.1.
Epitope
C terminus
Specificity
Reported variants represent identical protein: NP_064719.1 NP_064731.1 NP_064720.1 NP_064730.1
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
ABCD4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.3 - 1 ug/ml
  • Peptide ELISA Detection limit 1:8000
Application Notes
WB: Approx. 70 kDa band observed in lysates of Jurkat and MOLT4 (calculated MW of 68.6 kDa band according to NP_005041.1).
Publications
Read Publication using NBP1-20872.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat, Canine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ABCD4 Antibody

  • ATP-binding cassette sub-family D member 4
  • ATP-binding cassette, sub-family D (ALD), member 4
  • EST352188
  • P70R69 kDa peroxisomal ABC-transporter
  • Peroxisomal membrane protein 1-like
  • Peroxisomal membrane protein 69
  • PMP69P79R
  • PMP70-related protein
  • PXMP1-L
  • PXMP1LABC41

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ABCD4 Antibody (NBP1-20872)(1)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ABCD4
Entrez
Uniprot