Fibrinopeptide A Antibody (26-E7)

Product Discontinued

Fibrinopeptide A Antibody (26-E7) Summary

• Immunogen: fibrinopeptide A conjugated with a carrier protein.
• Specificity: Fibrinopeptide A region in the alpha-chain of fibrinogen and free fibrinopeptide A.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: FGA
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 1:100-1:2000
  • Western Blot 1:500-1:2000
• Application Notes: Recommended pairs for sandwich immunoassay (capture-detection): NB100-73042 - NB200-420

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for Fibrinopeptide A Antibody (26-E7)

• FGA
• Fib2
• Fibrinogen A
• Fibrinogen alpha chain
• Fibrinogen alpha subunit
• Fibrinogen Type I
• fibrinogen, A alpha polypeptide
• FPA
• MGC119422
• MGC119423
• MGC119425

Background

Fibrinogen is the main protein of the blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A and B are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerisation forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FGA
• Entrez:
  • 2243(Human)
  • 238644(Mouse)