5-HT7 Antibody

Product Discontinued

5-HT7 Antibody Summary

• Immunogen: Synthetic 14 amino acid peptide from N-terminus of human 5HT7 Receptor.
• Epitope: N-terminal domain of human
• Specificity: Human 5HT7 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except LTBR (50%).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HTR7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Marmoset (100%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 0.6 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for 5-HT7 Antibody

• 5HT7
• 5-HT7
• 5-HT-7
• 5-HT75-hydroxytryptamine receptor 7
• 5-HT-X
• 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
• HTR7
• serotonin 5-HT-7 receptor
• Serotonin receptor 7

Background

The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HTR7
• Entrez:
  • 3363(Human)