5-HT2B Antibody (2880B) [Allophycocyanin]

HEK293 cell transfected with 5-HT2B and eGFP vs irrelevant was stained with eGFP and Rabbit Anti-Human 5-HT2B APC‑conjugated Monoclonal Antibody (Catalog # FAB11297A) in 5-HT2B transfectants (A) or (B) irrelevant transfectants. View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Hu
• Applications: Flow
• Clone: 2880B
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Allophycocyanin

5-HT2B Antibody (2880B) [Allophycocyanin] Summary

• Immunogen: Synthetic peptide containing human 5- HTR2B
  Accession # P41595
• Specificity: Detects human 5-HTR2B in direct ELISA.
• Source: N/A
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity Statement: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for 5-HT2B Antibody (2880B) [Allophycocyanin]

• 5-HT(2B)
• 5HT2B
• 5-HT2B
• 5-HT-2B
• 5-HT2B5-HT 2B receptor
• 5-hydroxytryptamine (serotonin) receptor 2B
• 5-hydroxytryptamine 2B receptor
• 5-hydroxytryptamine receptor 2B
• HTR2B
• Serotonin receptor 2B

Background

HTR2B is a G-protein coupled receptor for serotonin. The 5HT2 receptors mediate many of the central and peripheral physiologic functions of serotonin. 5HT2B plays a role in the regulation of dopamine and serotonin release, serotonin uptake and in the regulation of extracellular dopamine and serotonin levels. It also plays a role in pulmonary vasoconstriction and regulating cardiac structure and functions. 5HT2B receptors were shown to be expressed in human failing heart and have been strongly implicated in drug induced valvular heart disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • P41595()