14-3-3 gamma Antibody (505810) [Alexa Fluor® 488]

• Applications: WB
• Clone: 505810
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

14-3-3 gamma Antibody (505810) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human 14-3-3γ
  Met1-Asn247
  Accession # P61981
• Specificity: Detects human, mouse, and rat 14-3-3 gamma in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

14-3-3 proteins are a highly conserved family of homo- and heterodimeric phosphoserine/threonine-binding proteins present in all eukaryotic cells. 14-3-3 proteins act as key regulators of intracellular signal transduction through their ability to bind specific motifs phosphorylated on serine or threonine. There are at least 7 distinct mammalian 14-3-3 genes: alpha / beta , epsilon , eta , gamma , tau / theta , sigma , and zeta /δ. 14-3-3 gamma becomes phosphorylated in response to PDGF and subsequently interacts with different PKC isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.