IL-1 alpha/IL-1F1 Products

Description

Interleukin-1 alpha (IL-1a, lymphocyte activating factor (LAF), hematopoietin-1, endogeneous pyrogen, mononuclear cell factor) is a pleiotropic pro-inflammatory cytokine produced in a variety of cells, including monocytes, macrophages and epithelial cells. It is involved in inflammatory and immune responses and regulation of hematopoiesis. It may therefore be of clinical use following massive immunosuppression and chemotherapy. Recombinant human IL-1a is a single non-glycosylated polypetide chain of 159 amino acids with a MW of 18 kDa. Sequence conservation of the mature protein among various species is 60% -70%, human IL-1 has been found to be biologically active on murine cell lines.

Bioinformatics

Entrez	16175 Mouse 24493 Rat 3552 Human
Uniprot	AAH13142 Human NP_000566 Human NP_000566.3 Human P01583 Human Q53QF9 Human Q62161 Mouse Q9NPH3 Human
Product By Gene ID	3552
Alternate Names	Hematopoietin-1 IL-1 alpha IL1 IL-1A IL1-ALPHA IL1F1hematopoietin-1 interleukin 1, alpha interleukin-1 alpha preinterleukin 1 alpha pro-interleukin-1-alpha

Research Areas for IL-1 alpha/IL-1F1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Biologically Active Proteins
Cytokine Research
Diabetes Research
Immune System Diseases
Immunology
Innate Immunity