Ephrin B2 Products

Antibodies
Ephrin-B2 Antibody [Unconjuga ...
Ephrin-B2 Antibody [Unconjugated]
AF496
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Ephrin B2 Antibody
Ephrin B2 Antibody
NBP1-84830
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Ephrin-B2 Antibody
Ephrin-B2 Antibody
AF1088
Species: Ze
Applications: WB
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Lysates
Ephrin B2 Overexpression Lysa ...
Ephrin B2 Overexpression Lysate (N...
NBL1-10147
Applications: WB
Proteins
Ephrin B2 Recombinant Protein ...
Ephrin B2 Recombinant Protein Antigen
NBP1-84830PEP
Species: Hu
Applications: AC
Ephrin-B2 Recombinant Protein ...
Ephrin-B2 Recombinant Protein
NBP2-52212
Species: Mu
Applications: PAGE
Ephrin B2 Recombinant Protein ...
Ephrin B2 Recombinant Protein
NBP1-72462
Species: Hu
Applications: PAGE
RNAi
Ephrin B2 RNAi
Ephrin B2 RNAi
H00001948-R01
Species: Hu

Description

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP)and also interacts with PRKCABP and GRIP1. This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. Ephrin-B2 also binds EphA4, EphB1, EphB2, EphB3 and EphB4. Ephrin-B2 can be detected on monocytes, mesangial cells, CD34+ stem cells, bone marrow fibroblasts, activated melanocytes and melanoma cells, and pre-artery endothelial cell.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 1948
Alternate Names
  • MGC126227
  • HTK-L
  • MGC126226
  • ligand of eph-related kinase 5
  • Htk-L
  • EPLG5HTK ligand
  • LERK5LERK-5
  • HTKLEPH-related receptor tyrosine kinase ligand 5
  • MGC126228
  • ephrin-B2

Research Areas for Ephrin B2

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Signal Transduction

PTMs for Ephrin B2

Learn more about PTMs related to Ephrin B2.

Phosphorylation
Methylation
Cleavage
Acetylation

Bioinformatics Tool for Ephrin B2

Discover related pathways, diseases and genes to Ephrin B2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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