ATG7 Products

Antibodies
ATG7 Antibody (SC06-30)
ATG7 Antibody (SC06-30)
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal
ATG7 Antibody
ATG7 Antibody
NB600-1274
Species: Hu, Mu, Rt, Ca, Ch, Pm
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Antibody Pairs
ATG7 Antibody Pair
ATG7 Antibody Pair
H00010533-PW1
Species: Hu
Applications: WB, IP
Lysates
ATG7 Overexpression Lysate
ATG7 Overexpression Lysate
NBL1-07800
Species: Hu
Applications: WB
Proteins
Recombinant Human His6-ATG7 I ...
Recombinant Human His6-ATG7 Isofor...
E-318
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
ATG7 Recombinant Protein Anti ...
ATG7 Recombinant Protein Antigen
NBP1-89042PEP
Species: Hu
Applications: AC
ATG7 Blocking Peptide
ATG7 Blocking Peptide
NBP1-96759
Species: Hu
Applications: AC

Description

FUNCTION: Functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. Forms intermediate conjugates with GABARAPL1 (GABARAPL2, GABARAP or MAP1ALC3). Formation of the final GABARAPL1-PE conjugate is essential for autophagy. SUBUNIT: Homodimer (By similarity). Interacts with ATG3 and ATG12. The complex, composed of ATG3 and ATG7, plays a role in the conjugation of ATG12 to ATG5. SUBCELLULAR LOCATION: Cytoplasm (Probable). ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Widely expressed, especially in kidney, liver, lymph nodes and bone marrow. DOMAIN: The C-terminal part of the protein is essential for the dimerization and interaction with ATG3 and ATG12. SIMILARITY: Belongs to the ATG7 family.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 10533
Alternate Names
  • ATG12-activating enzyme E1 ATG7
  • APG7-like
  • APG7L
  • ubiquitin-like modifier-activating enzyme ATG7
  • Ubiquitin-activating enzyme E1-like protein
  • ubiquitin activating enzyme E1-like protein
  • Autophagy-related protein 7
  • APG7-LIKE
  • GSA7
  • APG7 autophagy 7-like (S. cerevisiae)
  • DKFZp434N0735
  • hAGP7
  • ATG7 autophagy related 7 homolog (S. cerevisiae)

Research Areas for ATG7

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Phospho-Specific

Bioinformatics Tool for ATG7

Discover related pathways, diseases and genes to ATG7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related ATG7 Blog Posts

Check out the latest blog posts on ATG7.
Animal Models to Study Autophagy
By Christina Towers, PhD What is autophagy?Autophagy is the catabolic process that degrades cytoplasmic material via the lysosome. In the beginning... the process of macroautophagy was originally characterized in...    Read more.
Monitoring Autophagy in Neurons
By Christina Towers, PhD. Autophagy is a critical cellular process used by most cells in the body to recycle nutrients and prevent harmful buildup of damaged proteins. It is particularly important in the brain, where...    Read more.
Autophagy independent roles of the core ATG proteins
By Christina Towers, PhD. Autophagy and ATG ProteinsAutophagy is a nutrient recycling process that cells use to fuel metabolism, particularly in response to nutrient deprivation.  It is critical for removal of dam...    Read more.
Nuclear LC3: Why is it there and what is it doing?
By Christina Towers, PhD. Cells use the complex process of autophagy to degrade and recycle cytoplasmic material.  There are over 20 proteins that have been implicated in this process and appropriately named core...    Read more.
From Then ‘till Now: The History of Autophagy and Cancer Research
By Christina Towers, PhD. The fundamental process that cells use to degrade damaged cytoplasmic material and recycle nutrients is called autophagy.  This term was first coined by the Belgium biochemist Christian de...    Read more.
ATG4B - a cysteine protease involved in autophagosome elongation
Autophagy can be broken down into 4 main stages: phagophore nucleation, autophagosome elongation, autophagosome docking and fusion with a lysosome, and vesicle breakdown and degradation. ATG4B is one of four ATG4 homologs (ATG4A, ATG4B, ATG4C, and...    Read more.
ATG7 - an E1 enzyme for the ubiquitin-like autophagy proteins
Autophagy is an essential cellular process that maintains homeostasis through the degradation and recycling of cytoplasmic organelles and macromolecules. Substrates targeted for autophagy are engulfed in a double-membrane structure called the auto...    Read more.
ATG12 - a ubiquitin-like protein essential for autophagosome assembly
Atg12 is a ubiquitin-like protein that plays an essential role in cellular homeostasis by regulating the degradation and recycling of cytoplasmic organelles and macromolecules. Atg12 is one of two ubiquitin-like protein systems that is required du...    Read more.
Essential to Death: ATG5 (autophagy protein 5, apoptosis-specific protein ASP)
The ATG5 protein belongs to the ATG autophagy regulator family. This family controls the highly conserved cell's homeostatic response to a wide variety of both self- and foreign-originating cellular stimuli. ATG5 itself is ubiquitously expressed in mo...    Read more.
Read more ATG7 related blogs.