ATG7 Products

Antibodies
ATG7 Antibody
ATG7 Antibody
NBP2-24682
Species: Hu
Applications: WB, IHC-P
Host: Rabbit Polyclonal
ATG7 Antibody (683906) [Uncon ...
ATG7 Antibody (683906) [Unconjugated]
MAB6608
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, ICC
Host: Mouse Monoclonal
ATG7 Antibody
ATG7 Antibody
NB600-1274
Species: Hu, Canine, Chicken, Mouse, Rat
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Antibody Pairs
ATG7 Antibody Pair
ATG7 Antibody Pair
H00010533-PW1
Species: Hu
Applications: WB, IP
Lysates
ATG7 Overexpression Lysate (N ...
ATG7 Overexpression Lysate (Native)
NBL1-07800
Applications: WB
ATG7 Overexpression Lysate (D ...
ATG7 Overexpression Lysate (Denatu...
H00010533-T01
Applications: WB
Proteins
ATG7 Recombinant Protein
ATG7 Recombinant Protein
H00010533-P01
Species: Hu
Applications: WB, ELISA, PA
ATG7 Partial Recombinant Prot ...
ATG7 Partial Recombinant Protein
H00010533-Q01
Species: Hu
Applications: WB, ELISA, PA
ATG7 Recombinant Protein Anti ...
ATG7 Recombinant Protein Antigen
NBP1-89042PEP
Species: Hu
Applications: AC

Description

FUNCTION: Functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. Forms intermediate conjugates with GABARAPL1 (GABARAPL2, GABARAP or MAP1ALC3). Formation of the final GABARAPL1-PE conjugate is essential for autophagy. SUBUNIT: Homodimer (By similarity). Interacts with ATG3 and ATG12. The complex, composed of ATG3 and ATG7, plays a role in the conjugation of ATG12 to ATG5. SUBCELLULAR LOCATION: Cytoplasm (Probable). ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Widely expressed, especially in kidney, liver, lymph nodes and bone marrow. DOMAIN: The C-terminal part of the protein is essential for the dimerization and interaction with ATG3 and ATG12. SIMILARITY: Belongs to the ATG7 family.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 10533
Alternate Names
  • ATG12-activating enzyme E1 ATG7
  • APG7-like
  • APG7L
  • ubiquitin-like modifier-activating enzyme ATG7
  • Ubiquitin-activating enzyme E1-like protein
  • ubiquitin activating enzyme E1-like protein
  • Autophagy-related protein 7
  • APG7-LIKE
  • GSA7
  • APG7 autophagy 7-like (S. cerevisiae)
  • DKFZp434N0735
  • hAGP7
  • ATG7 autophagy related 7 homolog (S. cerevisiae)

Research Areas for ATG7

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Phospho-Specific

Bioinformatics Tool for ATG7

Discover related pathways, diseases and genes to ATG7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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Related ATG7 Blog Posts

Check out the latest blog posts on ATG7.
ATG4B - a cysteine protease involved in autophagosome elongation
Autophagy can be broken down into 4 main stages: phagophore nucleation, autophagosome elongation, autophagosome docking and fusion with a lysosome, and vesicle breakdown and degradation. ATG4B is one of four ATG4 homologs (ATG4A, ATG4B, ATG4C, and...    Read more.
ATG7 - an E1 enzyme for the ubiquitin-like autophagy proteins
Autophagy is an essential cellular process that maintains homeostasis through the degradation and recycling of cytoplasmic organelles and macromolecules. Substrates targeted for autophagy are engulfed in a double-membrane structure called the auto...    Read more.
ATG12 - a ubiquitin-like protein essential for autophagosome assembly
Atg12 is a ubiquitin-like protein that plays an essential role in cellular homeostasis by regulating the degradation and recycling of cytoplasmic organelles and macromolecules. Atg12 is one of two ubiquitin-like protein systems that is required du...    Read more.
Essential to Death: ATG5 (autophagy protein 5, apoptosis-specific protein ASP)
The ATG5 protein belongs to the ATG autophagy regulator family. This family controls the highly conserved cell's homeostatic response to a wide variety of both self- and foreign-originating cellular stimuli. ATG5 itself is ubiquitously expressed in mo...    Read more.
Read more ATG7 related blogs.