Caspase-1 Products

Description

Caspase-1 (ICE (IL-1b converting enzyme)) is similar to the cell death gene CED-3 of Caenorhabditilis elegans and regulates multiple proinflammatory cytokines, including interleukin-1b and interferon-gamma-inducing factor.

Bioinformatics

Entrez	834 Human 12362 Mouse 25166 Rat
Uniprot	NM_033292 Human NM_033293 Human P29466 Human AAH62327 Human NP_150634 Human NP_150634.1 Human NP_150635.1 Human NP_150636 Human
Product By Gene ID	834
Alternate Names	IL1BC CASP1 nirs variant 1 EC 3.4.22.36 EC 3.4.22 IL-1 beta-converting enzyme p45 IL-1BC IL1BCE CASP-1 interleukin 1-beta convertase Interleukin-1 beta-converting enzyme interleukin 1-B converting enzyme Interleukin-1 beta convertase caspase-1 caspase 1, apoptosis-related cysteine protease (interleukin 1, beta ICEP45 IL1B-convertase caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta

Diseases related to Caspase-1

Discover more about diseases related to Caspase-1.

Inflammation
Malignant Neoplasms
Neoplasms
Infective Disorder
Cell Transformation, Neoplastic
Carcinoma
Salmonella Infections
Malignant Neoplasm Of Breast
Coronary Artery Disease
Inflammatory Response
Colorectal Cancer
Innate Immune Response
Immunologic Deficiency Syndromes
Infarction
Myocardial Infarction
Tissue Adhesions
Atherosclerosis
Hyperplasia
Colitis
Systemic Infection

Pathways for Caspase-1

View related products by pathway and learn more about each of the pathways below.

Cell Death
Pathogenesis
Secretion
Immune Response
Localization
Cell Proliferation
Inflammatory Response
Pyroptosis
Cell Cycle
Innate Immune Response
Cell Adhesion
Cell Activation
Dna Methylation
Dna Repair
Methylation
Angiogenesis
Cell Migration
Chemokine Production
Cell Wall Modification
Dna Hypomethylation

Research Areas for Caspase-1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Caspases

PTMs for Caspase-1

Learn more about PTMs related to Caspase-1.

Cleavage
Phosphorylation
Methylation

Bioinformatics Tool for Caspase-1

Discover related pathways, diseases and genes to Caspase-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 

Related Caspase-1 Blog Posts

Check out the latest blog posts on Caspase-1.

NLRP3/NALP3 - Sensing and responding to pathogen infection The inflammasome is a multi protein complex that is an important component of the innate immune response. The inflammasome is able to sense and respond to pathogen infections by recognizing pathogen-associated molecular patterns and mediating the ...    Read more.

Caspase 10 - an initiator caspase in the extrinsic death receptor pathway Apoptosis, also called programmed cell death, is an essential process in development and disease. The signaling networks that carry out apoptosis is consists of a series of endoproteases called caspases which are synthesized as inactive zymogens....    Read more.

Caspase 7 - A key effector of the apoptotic pathway Caspase-7 is an effector caspase with important roles in mediating cell death signaling. As an effector caspase, caspase-7 is cleaved and activated by initiator caspases such as caspase-1 (1). Like other caspase family proteins, caspase-7 contains a...    Read more.

Caspase 1 - activating innate immune responses following infection or injury Caspase-1 is an enzyme involved in the conversion of interleukin-1 into its active secreted form. Interleukin-1 mediates inflammatory responses during infection and disease. Caspase-1 is recruited to and activated by the inflammasome complex (1). Un...    Read more.

Caspase-4 - a human protease with roles in inflammation and immunity Caspases are a family of cysteine-aspartic acid proteases that cleave caspase proenzymes as well as other protein substrates. Caspases are well known for their role in apoptosis, but they also play a significant role in other cellular processes inc...    Read more.

Read more Caspase-1 related blogs.