XK X-linked Kx blood group Antibody

Immunohistochemistry-Paraffin: XK X-linked Kx blood group Antibody [NBP1-50522] - Analysis of anti-XK antibody with human pancreas at concentration 10 ug/ml.

Immunohistochemistry-Paraffin: XK X-linked Kx blood group Antibody [NBP1-50522] - Analysis of anti-XK antibody with human pancreas at concentration 10 ug/ml.

Product Discontinued

XK X-linked Kx blood group Antibody Summary

• Immunogen: Synthetic peptide from human XK X-linked Kx blood group.
• Specificity: KLH conjugated synthetic peptide comprising amino acids 22 - 38 [LSLSSTYRSGGDRMWQA] of the human McLeod syndrome-associated Kell blood group protein (XK) protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: XK
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:1000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Rat (82%),Canine (82%), Rabbit (82%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for XK X-linked Kx blood group Antibody

• Kell blood group precursor (McLeod phenotype)
• Kell complex 37 kDa component
• Kx antigen
• Kx
• membrane transport protein XK
• X1k
• XK, Kell blood group complex subunit (McLeod syndrome)
• XKR1XK-related protein 1
• X-linked Kx blood group (McLeod syndrome)
• XRG1

Background

This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: XK
• Entrez:
  • 7504(Human)
• Uniprot:
  • P51811(Human)