WDR79 Antibody

Western Blot: WDR79 Antibody [H00055135-B01P] - Analysis of WDR79 expression in transfected 293T cell line by WDR79 polyclonal antibody. Lane 1: WDR79 transfected lysate(60.28 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

WDR79 Antibody Summary

• Immunogen: WDR79 (AAH02336.1, 1 a.a. - 548 a.a.) full-length human protein. MKTLETQPLAPDCCPSDQDPAPAHPSPHASPMNKNADSELMPPPPERGDPPRLSPDPVAGSAVSQELREGDPVSLSTPLETEFGSPSELSPRIEEQELSENTSLPAEEANGSLSEEEANGPELGSGKAMEDTSGEPAAEDEGDTAWNYSFSQLPRFLSGSWSEFSTQPENFLKGCKWAPDGSCILTNSADNILRIYNLPPELYHEGEQVEYAEMVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTESGDEGEELGLPLLSTRHVHLECRLQLWWCGGAPDSSIPDDHQGEKGQGGTEGGVGELI
• Specificity: WDR79 - WD repeat domain 79,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: WRAP53
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. Use in immunprecipitation reported in scientific literature (PMID 25512560)

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for WDR79 Antibody

• FLJ10385
• TCAB1WDR79telomerase Cajal body protein 1
• WD repeat containing, antisense to TP53
• WD repeat domain 79
• WD repeat-containing protein 79
• WD40 protein Wrap53
• WD40 repeat-containing protein encoding RNA antisense to p53
• WD-encoding RNA antisense to p53

Background

WD-repeat domain 79 (WDR79) contains six WD (tryptophan-aspartate) repeat domains found in a number of proteins that function as adaptor molecules in signal transduction and cytoskeletal organization. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. The function of the WDR79 protein has not been characterized, however significant and consistent single nucleotide polymorphisms in the WDR79 gene have been found to be associated with ER negative breast cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for WDR79 Antibody (H00055135-B01P)(1)

Publication using H00055135-B01P

• Henriksson Sofia, Rassoolzadeh Hanif, Hedstrom Elisabeth et al. The scaffold protein WRAP53beta orchestrates the ubiquitin response critical for DNA double-strand break repair. Genes Dev. 2014-12-15 [PMID: 25512560] (IP, Human)

Bioinformatics

• Gene Symbol: WRAP53
• Entrez:
  • 55135(Human)
• Uniprot:
  • AAH02336.1(Human)