Vinexin Antibody

Western Blot: Vinexin Antibody [NBP2-20860] - Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE gel, diluted at 1:500.

Immunohistochemistry-Paraffin: Vinexin Antibody [NBP2-20860] - Immunohistochemical analysis of paraffin-embedded Colon ca, using antibody at 1:250 dilution.

Product Discontinued

Vinexin Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human Vinexin. The exact sequence is proprietary.
• Localization: Isoform Alpha: Cell junction (By similarity); Cytoplasm; cytoskeleton (By similarity); Isoform Beta: Cell junction (By similarity); Nucleus
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SORBS3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 75 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for Vinexin Antibody

• SCAM-1SH3-containing adapter molecule 1
• SCAM1vinexin beta (SH3-containing adaptor molecule-1)
• SH3D4VINEXIN
• sorbin and SH3 domain containing 3
• Sorbin and SH3 domain-containing protein 3
• vinexin

Background

The SORBS3 gene encodes 2 isoforms vinexin-alpha and -beta that are vinculin (VCL; MIM 193065)-binding cytoskeletal proteins involved in focal adhesion and cell-cell adhesion (Kioka et al., 1999 [PubMed 9885244]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: SORBS3
• Uniprot:
  • O60504(Human)