Vanilloid R1/TRPV1 Antibody Blocking Peptide

• Reactivity: Rt
• Applications: AC
• Concentration: 2.0 mg/ml

Vanilloid R1/TRPV1 Antibody Blocking Peptide Summary

• Description: A rat TRPV1 antibody blocking peptide (Synthetic).

  Amino Acid Sequence: RASLDSEESESPPQENSC

• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: TRPV1
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NB100-1617.
  
  For further blocking peptide related protocol, click here.
• Theoretical MW: 1.96 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 °C.
• Buffer: N/A
• Preservative: N/A
• Concentration: 2.0 mg/ml
• Purity: N/A

Alternate Names for Vanilloid R1/TRPV1 Antibody Blocking Peptide

• Capsaicin Receptor
• Osm-9-like TRP channel 1
• OTRPC1
• transient receptor potential cation channel subfamily V member 1
• transient receptor potential cation channel, subfamily V, member 1
• transient receptor potential vanilloid 1a
• transient receptor potential vanilloid 1b
• TRPV1
• Vanilloid R1
• Vanilloid receptor 1
• vanilloid receptor subtype 1
• VanilloidR1
• VR1
• VR1DKFZp434K0220

Background

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for Vanilloid R1/TRPV1 Protein (NB100-1617PEP)(2)

Publications using NB100-1617PEP

• Bouskila J, Micaelo-Fernandes C, Palmour RM et al. Transient receptor potential vanilloid type 1 is expressed in the horizontal pathway of the vervet monkey retina Sci Rep 2020-07-21 [PMID: 32694518]
• Sappington RM, Sidorova T, Long DJ et al. TRPV1: Contribution to Retinal Ganglion Cell Apoptosis Increased Intracellular Ca2+ with Exposure to Hydrostatic Pressure. Invest Ophthalmol Vis Sci;50(2):717-28. 2009-02-01 [PMID: 18952924]

Bioinformatics

• Gene Symbol: TRPV1