Vanilloid R1/TRPV1 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: Vanilloid R1/TRPV1 Antibody [NB300-122] - Staining of mouse inferior olive using Cy3-conjugated donkey anti-rabbit secondary antibodies (red color) and DAPI (blue) as a nuclear ...read more
Immunohistochemistry: Vanilloid R1/TRPV1 Antibody [NB300-122] - Dorsal Root Ganglion
Immunohistochemistry-Frozen: Vanilloid R1/TRPV1 Antibody [NB300-122] - TRPV1 Antibody staining of rat dorsal horn (dilution 1:100).

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF, IHC, IHC-Fr
Clonality
Polyclonal
Host
Guinea Pig
Conjugate
Unconjugated

Order Details

Vanilloid R1/TRPV1 Antibody Summary

Immunogen
Synthetic peptide (YTGSLKPEDAEVFKDSMVPGEK) corresponding to residues aa 817-836 of the carboxy-terminus of rat TPVR1.
Isotype
IgG
Clonality
Polyclonal
Host
Guinea Pig
Gene
TRPV1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:50-1:200
Application Notes
IHC-Frozen, ICC/IF reactivity reported (PMID: 22998799).
Reviewed Applications
Read 1 Review rated 4
using
NB300-122 in the following applications:

Publications
Read Publications using
NB300-122 in the following applications:

Reactivity Notes

Mouse reactivity per customer review.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.05% Sodium Azide
Purity
Unpurified

Alternate Names for Vanilloid R1/TRPV1 Antibody

  • Capsaicin Receptor
  • Osm-9-like TRP channel 1
  • OTRPC1
  • transient receptor potential cation channel subfamily V member 1
  • transient receptor potential cation channel, subfamily V, member 1
  • transient receptor potential vanilloid 1a
  • transient receptor potential vanilloid 1b
  • TRPV1
  • Vanilloid R1
  • Vanilloid receptor 1
  • vanilloid receptor subtype 1
  • VanilloidR1
  • VR1
  • VR1DKFZp434K0220

Background

VR1 (vanilloid receptor 1) is an ion channel activated by capsaicin, the pungent ingredient in hot peppers, and by noxious thermal heat. It is expressed by and isolated from nociceptive sensory neurons. Sequence analysis suggests that VR1 has transmembrane domains and intracellular N- and C-termini. It shares structural similarities with the family of putative store-operated calcium channels. It is thought to function as a transducer of noxious thermal stimuli and have involvement in inflammatory pain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Vanilloid R1/TRPV1 Antibody (NB300-122)(4)

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 3 applications: ICC/IF, IHC, IHC-Fr.


Filter By Application
ICC/IF
(2)
IHC
(1)
IHC-Fr
(1)
All Applications
Filter By Species
Mouse
(1)
Rat
(2)
All Species

Review for Vanilloid R1/TRPV1 Antibody (NB300-122) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.

Reviews using NB300-122:
Filter by Applications
ICC
(1)
All Applications
Filter by Species
Mouse
(1)
All Species
Images Ratings Applications Species Date Details
Immunocytochemistry Vanilloid R1/TRPV1 NB300-122
Enlarge
4
reviewed by:
Temugin Berta
ICC Mouse 03/10/2017
View

Summary

ApplicationImmunocytochemistry
Sample TestedDorsal root ganglia
SpeciesMouse
Lot401615

Comments

CommentsBlocking and antibody solution: BSA1%/Triton 0.2% in PBS
Dilution TRPV1 antibody: 1/500
Secondary antibody: Alexa 488

Product General Protocols

View specific protocols for Vanilloid R1/TRPV1 Antibody (NB300-122): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for Vanilloid R1/TRPV1 Antibody (NB300-122). (Showing 1 - 1 of 1 FAQs).

  1. For the Vanilloid R1/TRPV1 antibody...does it bind intracellulary or extracellularly
    • This AB binds a.a region 817-826, which is a cytoplasmic domain according to uniprot:https://www.uniprot.org/uniprot/O35433#subcellular_location

Secondary Antibodies

 

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Diseases for Vanilloid R1/TRPV1 Antibody (NB300-122)

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Recent Reviews

4
5
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4
1
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1
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Temugin Berta
03/10/2017
Application: ICC
Species: Mouse

Bioinformatics

Gene Symbol TRPV1
Entrez
Uniprot