VAMP-1 Antibody (540524) [Alexa Fluor® 750]

• Reactivity: Hu, Mu
• Applications: WB, IHC
• Clone: 540524
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

VAMP-1 Antibody (540524) [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human VAMP-1
  Met1-Lys96
  Accession # P23763
• Specificity: Detects human and mouse VAMP-1/VAMP-2 in Western blots. This antibody does not react with recombinant VAMP family members 5, 7, and 8.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for VAMP-1 Antibody (540524) [Alexa Fluor® 750]

• DKFZp686H12131
• SYB1
• SYB1vesicle-associated membrane protein 1
• synaptobrevin 1
• Synaptobrevin-1
• VAMP1
• VAMP-1
• VAMP-1synaptobrevin-1
• vesicle-associated membrane protein 1 (synaptobrevin 1)

Background

VAMP-1 (vesicle-associated membrane protein 1; also synaptobrevin-1/SYB1) is an 18 kDa member of the synaptobrevin family of proteins. It is expressed in neurons, neutrophils and skeletal muscle cells, and participates in vesicle fusion with the plasma membrane. Human VAMP-1 is a type IV transmembrane protein that contains an N-terminal cytoplasmic region (aa 1‑96) and a 22 aa transmembrane domain (aa 97‑118). There is one coiled-coil region between aa 33‑93. Multiple splice variants are known that show two, three, four and 81 aa substitutions for the C-terminal five amino acids. One three aa variant creates a mitochondrial targeting motif. Over aa 1‑96, human VAMP-1 is 98% aa identical to mouse VAMP-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.