Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, ICC/IF
Host: Rabbit Monoclonal
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, S-ELISA
Host: Mouse Monoclonal
The Vesicle Associated Membrane Proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer®s disease, VAMP levels of all isoforms appear to be significantly lowered. It has been shown that the extreme carboxy-terminus of VAMP-1 is involved in subcellular vesicle targeting.
|Product By Gene ID
- SYB1vesicle-associated membrane protein 1
- synaptobrevin 1
- vesicle-associated membrane protein 1 (synaptobrevin 1)
Bioinformatics Tool for VAMP-1
Discover related pathways, diseases and genes to VAMP-1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.